Publications

  • Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, et al. Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nature genetics. 2017;49(3):403-15.
  • Wahl S, Drong A, Lehne B, Loh M, Scott WR, Kunze S, et al. Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature. 2017;541(7635):81-6.
  • Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, et al. The genetic architecture of type 2 diabetes. Nature. 2016;536(7614):41-7.
  • Loley C, Alver M, Assimes TL, Bjonnes A, Goel A, Gustafsson S, et al. No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Scientific reports. 2016;6:35278.
  • van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, et al. 52 Genetic Loci Influencing Myocardial Mass. Journal of the American College of Cardiology. 2016;68(13):1435-48.
  • Zhang W, Jerneren F, Lehne BC, Chen MH, Luben RN, Johnston C, et al. Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. Thrombosis and haemostasis. 2016;116(6).
  • Ehret GB, Ferreira T, Chasman DI, Jackson AU. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. 2016;48(10):1171-84.
  • Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, et al. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. 2016;48(10):1151-61.
  • Kanoni S, Masca NG, Stirrups KE, Varga TV, Warren HR, Scott RA, et al. Analysis with the exome array identifies multiple new independent variants in lipid loci. Human molecular genetics. 2016.
  • Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, et al. Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genetics. 2016;12(6):e1006166.
  • Scott WR, Zhang W, Loh M, Tan ST, Lehne B, Afzal U, et al. Investigation of Genetic Variation Underlying Central Obesity amongst South Asians. PloS one. 2016;11(5):e0155478.
  • van Leeuwen EM, Sabo A, Bis JC, Huffman JE, Manichaikul A, Smith AV, et al. Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. Journal of medical genetics. 2016;53(7):441-9.
  • Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, et al. Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Human molecular genetics. 2016;25(10):2070-81.
  • Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, et al. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications. 2016;7:10495.
  • Heiss JA, Breitling LP, Lehne B, Kooner JS, Chambers JC, Brenner H. Training a model for estimating leukocyte composition using whole-blood DNA methylation and cell counts as reference. Epigenomics. 2016.
  • Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, et al. A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications. 2016;7:13357.
  • Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2015;11(10):e1005378.
  • Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, et al. Directional dominance on stature and cognition in diverse human populations. Nature. 2015;523(7561):459-62.
  • Lehne B, Drong AW, Loh M, Zhang W, Scott WR, Tan ST, et al. A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies. Genome biology. 2015;16:37.
  • Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, et al. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nature genetics. 2015;47(11):1282-93.
  • Nikpay M, Goel A, Won HH, Hall LM, Willenborg C, Kanoni S, et al. A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nature genetics. 2015;47(10):1121-30.
  • Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, et al. Directional dominance on stature and cognition in diverse human populations. Nature. 2015;523(7561):459-62.
  • Nelson CP, Hamby SE, Saleheen D, Hopewell JC, Zeng L, Assimes TL, et al. Genetically determined height and coronary artery disease. The New England journal of medicine. 2015;372(17):1608-18.
  • Chambers JC, Loh M, Lehne B, Drong A, Kriebel J, Motta V, et al. Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study. The lancet Diabetes & endocrinology. 2015;3(7):526-34.
  • Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197-206.
  • Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Magi R, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015;518(7538):187-96.
  • Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nature genetics. 2014;46(11):1173-86.
  • Chen L, Kostadima M, Martens JH, Canu G, Garcia SP, Turro E, et al. Transcriptional diversity during lineage commitment of human blood progenitors. Science (New York, NY). 2014;345(6204):1251033.
  • Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature genetics. 2014;46(3):234-44.
  • Chambers JC, Abbott J, Zhang W, Turro E, Scott WR, Tan ST, et al. The South Asian genome. PloS one. 2014;9(8):e102645.
  • Hoggart CJ, Venturini G, Mangino M, Gomez F, Ascari G, Zhao JH, et al. Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. PLoS Genet. 2014;10(7):e1004508.
  • Tan ST, Scott W, Panoulas V, Sehmi J, Zhang W, Scott J, et al. Coronary heart disease in Indian Asians. Global cardiology science & practice. 2014;2014(1):13-23.
  • Yaghootkar H, Scott RA, White CC, Zhang W, Speliotes E, Munroe PB, et al. Genetic evidence for a normal-weight “metabolically obese” phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes. Diabetes. 2014;63(12):4369-77.
  • Flannick J, Thorleifsson G, Beer NL, Jacobs SBR, Grarup N, Burtt NP, et al. Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nature genetics. 2014;46(4):357-63.
  • Xi B, Takeuchi F, Meirhaeghe A, Kato N, Chambers JC, Morris AP, et al. Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis. Clinical endocrinology. 2014;81(5):702-10.
  • Flannick J, Thorleifsson G, Beer NL, Jacobs SBR, Grarup N, Burtt NP, et al. Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nature genetics. 2014;46(4):357-63.
  • Dichgans M, Malik R, Konig IR, Rosand J, Clarke R, Gretarsdottir S, et al. Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Stroke. 2014;45(1):24-36.
  • Walker DG, Williams HR, Bancil AS, Rai P, Pantelidis P, Chambers J, et al. Ethnicity differences in genetic susceptibility to ulcerative colitis: a comparison of Indian asians and white northern Europeans. Inflammatory bowel diseases. 2013;19(13):2888-94.
  • Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, et al. Discovery and refinement of loci associated with lipid levels. Nature genetics. 2013;45(11):1274-83.
  • Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature genetics. 2013;45(11):1345-52.
  • O’Seaghdha CM, Wu H, Yang Q, Kapur K, Guessous I, Zuber AM, et al. Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genet. 2013;9(9):e1003796.
  • Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, et al. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 2013;128(12):1310-24.
  • van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, et al. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. The American journal of clinical nutrition. 2013;98(3):668-76.
  • Sabharwal S, Patel V, Nijjer SS, Kirresh A, Darzi A, Chambers JC, et al. Guidelines in cardiac clinical practice: evaluation of their methodological quality using the AGREE II instrument. Journal of the Royal Society of Medicine. 2013;106(8):315-22.
  • den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, et al. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature genetics. 2013;45(6):621-31.
  • Paul DS, Albers CA, Rendon A, Voss K, Stephens J, van der Harst P, et al. Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci. Genome research. 2013;23(7):1130-41.
  • Wang X, Chua HX, Chen P, Ong RT, Sim X, Zhang W, et al. Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies. Human molecular genetics. 2013;22(11):2303-11.
  • Saxena R, Saleheen D, Been LF, Garavito ML, Braun T, Bjonnes A, et al. Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. Diabetes. 2013;62(5):1746-55.
  • Kottgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, et al. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nature genetics. 2013;45(2):145-54.
  • Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nature genetics. 2013;45(1):25-33.
  • Chahal NS, Lim TK, Jain P, Chambers JC, Kooner JS, Senior R. The increased prevalence of left ventricular hypertrophy and concentric remodeling in U.K. Indian Asians compared with European whites. Journal of human hypertension. 2013;27(5):288-93.
  • Chaturvedi N, Bathula R, Shore AC, Panerai R, Potter J, Kooner J, et al. South Asians have elevated postexercise blood pressure and myocardial oxygen consumption compared to Europeans despite equivalent resting pressure. Journal of the American Heart Association. 2012;1(5):e000281.
  • Chahal NS, Lim TK, Jain P, Chambers JC, Kooner JS, Senior R. Population-based reference values for 3D echocardiographic LV volumes and ejection fraction. JACC Cardiovascular imaging. 2012;5(12):1191-7.
  • van der Harst P, Zhang W, Mateo Leach I, Rendon A, Verweij N, Sehmi J, et al. Seventy-five genetic loci influencing the human red blood cell. Nature. 2012;492(7429):369-75.
  • Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding J, et al. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood. 2012;120(24):4873-81.
  • Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, et al. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nature genetics. 2012;44(8):904-9.
  • Braun TR, Been LF, Singhal A, Worsham J, Ralhan S, Wander GS, et al. A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides. PloS one. 2012;7(5):e37056.
  • Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012;8(3):e1002607.
  • Sarwar N, Butterworth AS, Freitag DF, Gregson J, Willeit P, Gorman DN, et al. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (London, England). 2012;379(9822):1205-13.
  • Clarke R, Bennett DA, Parish S, Verhoef P, Dotsch-Klerk M, Lathrop M, et al. Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias. PLoS medicine. 2012;9(2):e1001177.
  • Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, et al. New gene functions in megakaryopoiesis and platelet formation. Nature. 2011;480(7376):201-8.
  • Li H, Kilpelainen TO, Liu C, Zhu J, Liu Y, Hu C, et al. Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia. 2012;55(4):981-95.
  • Hoggart CJ, O’Reilly PF, Kaakinen M, Zhang W, Chambers JC, Kooner JS, et al. Fine-scale estimation of location of birth from genome-wide single-nucleotide polymorphism data. Genetics. 2012;190(2):669-77.
  • Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, et al. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nature genetics. 2011;43(11):1131-8.
  • Kooner JS, Saleheen D, Sim X, Sehmi J, Zhang W, Frossard P, et al. Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nature genetics. 2011;43(10):984-9.
  • Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011;478(7367):103-9.
  • Wain LV, Verwoert GC, O’Reilly PF, Shi G, Johnson T, Johnson AD, et al. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nature genetics. 2011;43(10):1005-11.
  • Chahal NS, Lim TK, Jain P, Chambers JC, Kooner JS, Senior R. Does subclinical atherosclerosis burden identify the increased risk of cardiovascular disease mortality among United Kingdom Indian Asians? A population study. American heart journal. 2011;162(3):460-6.
  • Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, et al. Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes. 2011;60(10):2624-34.
  • Bathula R, Hughes AD, Panerai RB, Potter JF, Mc GTSA, Tillin T, et al. South Asians have adverse cerebrovascular haemodynamics, despite equivalent blood pressure, compared with Europeans. This is due to their greater hyperglycaemia. International journal of epidemiology. 2011;40(6):1490-8.
  • Kilpelainen TO, Zillikens MC, Stancakova A, Finucane FM, Ried JS, Langenberg C, et al. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nature genetics. 2011;43(8):753-60.
  • Facer P, Punjabi PP, Abrari A, Kaba RA, Severs NJ, Chambers J, et al. Localisation of SCN10A gene product Na(v)1.8 and novel pain-related ion channels in human heart. International heart journal. 2011;52(3):146-52.
  • Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, et al. Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proceedings of the National Academy of Sciences of the United States of America. 2011;108(17):7119-24.
  • Petit SJ, Wise EL, Chambers JC, Sehmi J, Chayen NE, Kooner JS, et al. The CXCL16 A181V mutation selectively inhibits monocyte adhesion to CXCR6 but is not associated with human coronary heart disease. Arteriosclerosis, thrombosis, and vascular biology. 2011;31(4):914-20.
  • Williams ED, Steptoe A, Chambers JC, Kooner JS. Ethnic and gender differences in the relationship between hostility and metabolic and autonomic risk factors for coronary heart disease. Psychosomatic medicine. 2011;73(1):53-8.
  • Waterworth DM, Ricketts SL, Song K, Chen L, Zhao JH, Ripatti S, et al. Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arteriosclerosis, thrombosis, and vascular biology. 2010;30(11):2264-76.
  • Chahal NS, Lim TK, Jain P, Chambers JC, Kooner JS, Senior R. The distinct relationships of carotid plaque disease and carotid intima-media thickness with left ventricular function. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. 2010;23(12):1303-9.
  • Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, et al. Common variants at 10 genomic loci influence hemoglobin A(1)(C) levels via glycemic and nonglycemic pathways. Diabetes. 2010;59(12):3229-39.
  • Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010;466(7307):707-13.
  • Kapur K, Johnson T, Beckmann ND, Sehmi J, Tanaka T, Kutalik Z, et al. Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. PLoS Genet. 2010;6(7):e1001035.
  • Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, Middleton L, et al. Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nature genetics. 2010;42(5):436-40.
  • Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, et al. Genetic loci influencing kidney function and chronic kidney disease. Nature genetics. 2010;42(5):373-5.
  • Chambers JC, Zhao J, Terracciano CM, Bezzina CR, Zhang W, Kaba R, et al. Genetic variation in SCN10A influences cardiac conduction. Nature genetics. 2010;42(2):149-52.
  • Chahal NS, Lim TK, Jain P, Chambers JC, Kooner JS, Senior R. New insights into the relationship of left ventricular geometry and left ventricular mass with cardiac function: A population study of hypertensive subjects. European heart journal. 2010;31(5):588-94.
  • Chahal NS, Lim TK, Jain P, Chambers JC, Kooner JS, Senior R. Normative reference values for the tissue Doppler imaging parameters of left ventricular function: a population-based study. European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology. 2010;11(1):51-6.
  • Chambers JC, Zhang W, Li Y, Sehmi J, Wass MN, Zabaneh D, et al. Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nature genetics. 2009;41(11):1170-2.
  • Zabaneh D, Chambers JC, Elliott P, Scott J, Balding DJ, Kooner JS. Heritability and genetic correlations of insulin resistance and component phenotypes in Asian Indian families using a multivariate analysis. Diabetologia. 2009;52(12):2585-9.
  • Chambers JC, Zhang W, Zabaneh D, Sehmi J, Jain P, McCarthy MI, et al. Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians. Diabetes. 2009;58(11):2703-8.
  • Williams ED, Steptoe A, Chambers JC, Kooner JS. Psychosocial risk factors for coronary heart disease in UK South Asian men and women. Journal of epidemiology and community health. 2009;63(12):986-91.
  • Chahal NS, Lim TK, Jain P, Chambers JC, Kooner JS, Senior R. Ethnicity-related differences in left ventricular function, structure and geometry: a population study of UK Indian Asian and European white subjects. Heart (British Cardiac Society). 2010;96(6):466-71.
  • Elliott P, Chambers JC, Zhang W, Clarke R, Hopewell JC, Peden JF, et al. Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. Jama. 2009;302(1):37-48.
  • Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, et al. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet. 2009;5(6):e1000508.
  • Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, et al. Genome-wide association study identifies eight loci associated with blood pressure. Nature genetics. 2009;41(6):666-76.
  • Newhouse S, Farrall M, Wallace C, Hoti M, Burke B, Howard P, et al. Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion. PloS one. 2009;4(4):e5003.
  • Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nature genetics. 2009;41(1):56-65.
  • Yuan X, Waterworth D, Perry JR, Lim N, Song K, Chambers JC, et al. Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. American journal of human genetics. 2008;83(4):520-8.
  • Caulfield MJ, Munroe PB, O’Neill D, Witkowska K, Charchar FJ, Doblado M, et al. SLC2A9 is a high-capacity urate transporter in humans. PLoS medicine. 2008;5(10):e197.
  • Nelson MR, Bryc K, King KS, Indap A, Boyko AR, Novembre J, et al. The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. American journal of human genetics. 2008;83(3):347-58.
  • Chambers JC, Elliott P, Zabaneh D, Zhang W, Li Y, Froguel P, et al. Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nature genetics. 2008;40(6):716-8.
  • Kooner JS, Chambers JC, Aguilar-Salinas CA, Hinds DA, Hyde CL, Warnes GR, et al. Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nature genetics. 2008;40(2):149-51.
  • Tillin T, Dhutia H, Chambers J, Malik I, Coady E, Mayet J, et al. South Asian men have different patterns of coronary artery disease when compared with European men. International journal of cardiology. 2008;129(3):406-13.
  • Tillin T, Chambers J, Malik I, Coady E, Byrd S, Mayet J, et al. Measurement of pulse wave velocity: site matters. Journal of hypertension. 2007;25(2):383-9.
  • Chambers JC, Kooner JS. Diabetes, insulin resistance and vascular disease among Indian Asians and Europeans. Seminars in vascular medicine. 2002;2(2):199-214.
  • Chambers JC, Ueland PM, Wright M, Dore CJ, Refsum H, Kooner JS. Investigation of relationship between reduced, oxidized, and protein-bound homocysteine and vascular endothelial function in healthy human subjects. Circulation research. 2001;89(2):187-92.
  • Chambers JC, Kooner JS. Homocysteine: a novel risk factor for coronary heart disease in UK Indian Asians. Heart (British Cardiac Society). 2001;86(2):121-2.
  • Chambers JC, Eda S, Bassett P, Karim Y, Thompson SG, Gallimore JR, et al. C-reactive protein, insulin resistance, central obesity, and coronary heart disease risk in Indian Asians from the United Kingdom compared with European whites. Circulation. 2001;104(2):145-50.
  • Chambers JC, Kooner JS. Homocysteine–an innocent bystander in vascular disease? European heart journal. 2001;22(9):717-9.
  • Chambers JC, Wander GS, Kooner JS. Homocysteine and coronary heart disease amongst Indian Asians. Indian heart journal. 2000;52(7 Suppl):S5-8.
  • Chambers JC, Fusi L, Malik IS, Haskard DO, De Swiet M, Kooner JS. Association of maternal endothelial dysfunction with preeclampsia. Jama. 2001;285(12):1607-12.
  • Chambers JC, Seddon MD, Shah S, Kooner JS. Homocysteine–a novel risk factor for vascular disease. Journal of the Royal Society of Medicine. 2001;94(1):10-3.
  • Chambers JC, Haskard DO, Kooner JS. Vascular endothelial function and oxidative stress mechanisms in patients with Behcet’s syndrome. Journal of the American College of Cardiology. 2001;37(2):517-20.
  • Chambers JC, Ueland PM, Obeid OA, Wrigley J, Refsum H, Kooner JS. Improved vascular endothelial function after oral B vitamins: An effect mediated through reduced concentrations of free plasma homocysteine. Circulation. 2000;102(20):2479-83.
  • Chambers JC, Ireland H, Thompson E, Reilly P, Obeid OA, Refsum H, et al. Methylenetetrahydrofolate reductase 677 C–>T mutation and coronary heart disease risk in UK Indian Asians. Arteriosclerosis, thrombosis, and vascular biology. 2000;20(11):2448-52.
  • Chambers JC, Obeid OA, Refsum H, Ueland P, Hackett D, Hooper J, et al. Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men. Lancet (London, England). 2000;355(9203):523-7.
  • Chambers JC, Obeid OA, Kooner JS. Physiological increments in plasma homocysteine induce vascular endothelial dysfunction in normal human subjects. Arteriosclerosis, thrombosis, and vascular biology. 1999;19(12):2922-7.
  • Chambers JC, McGregor A, Jean-Marie J, Kooner JS. Abnormalities of vascular endothelial function may contribute to increased coronary heart disease risk in UK Indian Asians. Heart (British Cardiac Society). 1999;81(5):501-4.
  • Chambers JC, McGregor A, Jean-Marie J, Obeid OA, Kooner JS. Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy. Circulation. 1999;99(9):1156-60.
  • Michie CA, Chambers J, Abramsky L, Kooner JS. Folate deficiency, neural tube defects, and cardiac disease in UK Indians and Pakistanis. Lancet (London, England). 1998;351(9109):1105.
  • Chambers JC, McGregor A, Jean-Marie J, Kooner JS. Acute hyperhomocysteinaemia and endothelial dysfunction. Lancet (London, England). 1998;351(9095):36-7.
  • Coronary Artery Disease (C4D) Genetics Consortium..A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. Nat Genet. 2011 Mar 6;43(4):339-44.